Higher blood sugar tied to COVID-19 death risk; rise in U.S. overdose deaths may have pandemic link

[Eugene]

Source: Reuters

RACE FOR A CURE
DECEMBER 5, 2020 5:36 PM UPDATED 17 HOURS AGO

Higher blood sugar tied to COVID-19 death risk; rise in U.S. overdose deaths may have pandemic link

By Nancy Lapid
5 MIN READ

(Reuters) - The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

High blood sugar tied to COVID-19 risk in nondiabetics

High blood sugar may portend a rocky course for COVID-19 patients who seek hospital care, even if they do not have diabetes, according to a new study of 11,000 COVID-19 patients in Spain. None were critically ill when they got to the hospital. But researchers found those who arrived with above-normal blood sugar levels had higher odds of dying there - regardless of whether they were diabetic. Overall, 20% of the patients died while hospitalized, including 16% of individuals with blood sugar below 140 milligrams per deciliter at admission, 34% of those with levels of 140 to 180 mg/dL, and 41% of patients with levels above 180 mg/dL. (A level of 200 mg/dL or higher indicates diabetes.) After taking age and medical conditions into account, patients with the highest levels were 50% more likely to die in the hospital than patients with the lowest levels. People with elevated blood sugar were also at higher risk for needing intensive care and mechanical breathing assistance. In a report published on Tuesday in Annals of Medicine, the researchers say prompt control of blood sugar should be mandatory in the management of patients hospitalized with COVID-19, regardless of whether they have diabetes.

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Read more: https://www.reuters.com/article/us-health-coronavirus-science/higher-blood-sugar-tied-to-covid-19-death-risk-rise-in-u-s-overdose-deaths-may-have-pandemic-link-idUSKBN28F0WS

[Phoenix61]

1. Not surprising that prediabetes would be a risk factor.

“For those without diabetes, normal blood sugar levels are considered between 70 to 99 mg/dL after fasting, and less than 140 after eating.”

[question everything]

2. At the same time, though metformin, a generic drug commonly used for managing blood sugar

diabetes patients, was associated with significantly reduced risk of COVID-19 death in women.

The retrospective study published in the Lancet Healthy Longevity looked at about 6,000 patients with Type 2 diabetes or obesity who were hospitalized with COVID-19. It found that women who had filled a 90-day prescription before hospitalization had a 21% to 24% reduced likelihood of mortality compared with women in the study who weren’t taking the medicine. There wasn’t a significant reduction in mortality among men, according to results that originally were released in June.

https://www.startribune.com/as-case-counts-stabilize-covid-deaths-in-minn-are-surging/573304591/