Research reveals toxic PFAS 'forever chemicals' accumulate in testes

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Related: Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome (ScienceDirect)

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Source: The Guardian

Research reveals toxic PFAS ‘forever chemicals’ accumulate in testes

Study suggests exposure to chemicals manufactured to resist water and heat likely to affect health of offspring

Tom Perkins
Sat 22 Jun 2024 14.00 BST
Last modified on Sat 22 Jun 2024 14.02 BST

New research has found for the first time that PFAS “forever chemicals” accumulate in the testes, and the exposure probably affects children’s health.

The toxic chemicals can damage sperm during a sensitive developmental period, potentially leading to liver disease and higher cholesterol, especially in male offspring, the paper, which looked at the chemicals in mice, noted.

The research is part of a growing body of work that highlights how paternal exposure to toxic chemicals “can really impact the health, development and future diseases of the next generation”, said Richard Pilsner, a Wayne State University School of Medicine researcher who co-authored the study.

“We’ve always been concerned with maternal environmental health effects because women gestate the babies … but this research is really saying there is a paternal contribution to offspring health and development,” Pilsner added.

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Read more: https://www.theguardian.com/environment/article/2024/jun/22/toxic-pfas-chemicals-testes