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Former_DU_Member

(33 posts)
12. There may be other avenues available to you... mind you this
Tue Feb 28, 2012, 08:22 PM
Feb 2012

is a very recent paper, however there are others yet at Pubmed.

http://www.ncbi.nlm.nih.gov/pubmed/22329607
Drugs R D. 2012 Feb 13. doi: 10.2165/11599200-000000000-00000. [Epub ahead of print]
Combination of Alpha Lipoic Acid and Superoxide Dismutase Leads to Physiological and Symptomatic Improvements in Diabetic Neuropathy.
Bertolotto F, Massone A.
Source

Neurophysiology Laboratory, Spine Unit at Santa Corona Hospital, Pietra Ligure, Savona, Italy.
Abstract

Background and Objective: The management of diabetic neuropathy is still a challenge for physicians. The aim of this study was to assess the efficacy of a new combination of alpha lipoic acid and superoxide dismutase for the treatment of diabetic neuropathy. Methods: The setting of this study was ambulatory (outpatient) care. A prospective, non-randomized, open-label study was conducted in 50 patients with diabetes mellitus and with a deficit in both motor and sensory nerve conduction.

Treatment was with a new combination of alpha lipoic acid and superoxide dismutase (ALA600SOD®) for 4 months. Electroneurographic parameters and perceived pain were assessed at baseline and after treatment. Results: After 4 months of treatment, patients significantly (p < 0.001) improved their electroneurographic parameters and their perception of pain. Best improvements were observed in sensory nerve conduction.

Conclusion: The combination of two powerful antioxidant agents leads to improvement in both subjective and objective parameters in patients with diabetic neuropathy. New profitable directions for investigations are opened for a non-invasive treatment of diabetic neuropathy in the future.

Recommendations

0 members have recommended this reply (displayed in chronological order):

a teenie weenie one. mopinko Feb 2012 #1
I have never been given lyrica Irishonly Feb 2012 #6
I am on no medication for it Irishonly Jul 2012 #15
Yes, I have severe neuropathy CountAllVotes Feb 2012 #2
I wear the duragesic patch Irishonly Feb 2012 #3
I tried that briefly CountAllVotes Feb 2012 #4
My body will not tolerate methadone or morphine Irishonly Feb 2012 #5
There may be other avenues available to you... mind you this Former_DU_Member Feb 2012 #12
i gained some weight at first with it. mopinko Feb 2012 #7
Oh, hell, yeah libodem Feb 2012 #8
It sounds like Charcot Marie Tooth disease. zanana1 Feb 2012 #9
I have a failed fusion in my lower back libodem Feb 2012 #10
Mine is mild compared to what you go through Irishonly Feb 2012 #11
Type one diabetic for 30 years and dealing with nueropathy for the past 11 rl6214 Jul 2012 #13
How does it work for you? Irishonly Jul 2012 #16
I started on neurontin years ago when first diagnosed but it didn't work for long rl6214 Jul 2012 #17
When MSN had groups, I belonged to a neuropathy group Irishonly Jul 2012 #20
This message was self-deleted by its author KC Jul 2012 #14
I was recently diagnosed with dermatomyositis NightWatcher Jul 2012 #18
I am sorry to hear that. Irishonly Jul 2012 #19
This message was self-deleted by its author silentwarrior Oct 2012 #21
I am sorry Irishonly Oct 2012 #22
This message was self-deleted by its author silentwarrior Oct 2012 #23
Nothing does Irishonly Oct 2012 #24
I am KC Oct 2012 #25
Spam deleted by gkhouston (MIR Team) pareshaegis Oct 2012 #26
Me. greatauntoftriplets Nov 2012 #27
I am sorry Irishonly Nov 2012 #28
Thanks, Irishonly. greatauntoftriplets Nov 2012 #29
Can you wear socks with your shoes? Irishonly Nov 2012 #30
Yes, I'm in Chicago and have to wear socks in cold weather. greatauntoftriplets Nov 2012 #31
I sent you an email Irishonly Nov 2012 #32
Thanks very much. greatauntoftriplets Nov 2012 #33
I was looking on Amazon KC Jan 2013 #34
My daughter gave me some wool socks with arch supports for Christmas Irishonly Jan 2013 #35
Latest Discussions»Support Forums»Chronic Health Conditions Discussion and Support»Are there any neuropathy ...»Reply #12